Halfway by way of his career, Cees Dekker reinvented himself. Soon after many years of hardcore physics, he shifted his aim to ‘nanobiology’ on the transform in the millennium. A time period he coined himself, like a make any difference of reality.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
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2007, to start with actual-time detection of strand Trade in homologous recombination by RecA; discovery of a lower persistence duration of ends of microtubules; and solved the system of biosensing with carbon nanotubes
We develop issue-of-treatment diagnostics take a look at of neglected tropical diseases in just source-restricted settings, based upon Crspr/Cas9 detecting of pathogen’s DNA in human body fluids.
The coiled-coil from the human Rad50 DNA repair protein has certain segments of increased overall flexibility
MATLAB codes for details processing can be obtained at . Julia codes utilized for numerical simulation are offered at .
Atomic power microscopy demonstrates that vaccinia topoisomerase IB generates filaments on DNA in a cooperative style
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But carbon nanotubes have remained a investigation matter of significant curiosity to quite a few. In truth, the outlook on applying carbon nanotubes to create useful gadgets, in areas such as radio-frequency electronics, electronic electronics and flexible electronics, remains bright.
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Cees Dekker is Distinguished College Professor at TU Delft. Properly trained to be a physicist, he pioneered nanotechnology with lots of discoveries on carbon nanotubes in the nineteen nineties. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His latest investigate concentrates on (i) nanopores for protein sequencing; (ii) chromosome construction, particularly SMC motor protein; and (iii) building a dwelling artificial mobile from lifeless molecules. Dekker is undoubtedly an elected member on the KNAW and fellow on the APS plus the IOP.
2008, to start with observation of protein-coated DNA translocation as a result of nanopores; fixed the origin of your electrophoretic pressure on DNA in nanopores; learned a big velocity enhance of microtubules in electrical fields; found an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of sounds in carbon nanotubes in liquid
2004, discovery of new physics in translocation of DNA by nanopores; initial experimental analyze of ions conduction in nanofluidic channels; 1st electrochemistry with person one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization from the mechanical cees dekker Attributes of double-stranded RNA; and very first one-molecule examine of DNA translocation by a restriction-modification enzyme.